Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biotechnology tool
molecular biology technique |
| gptkbp:alternativeTo |
gptkb:Northern_blot
RNA-Seq qPCR |
| gptkbp:analyzes |
laser scanner
confocal microscope |
| gptkbp:component |
glass slide
DNA probes fluorescent labels hybridization chamber nylon membrane silicon chip |
| gptkbp:developedBy |
1990s
|
| gptkbp:format |
gptkb:MIAME
gptkb:GEO_(Gene_Expression_Omnibus) |
| https://www.w3.org/2000/01/rdf-schema#label |
DNA microarrays
|
| gptkbp:inventedBy |
gptkb:Patrick_O._Brown
gptkb:Stephen_Fodor |
| gptkbp:limitation |
limited dynamic range
cross-hybridization requires prior sequence knowledge |
| gptkbp:output |
gene expression data
genotype data copy number variation data |
| gptkbp:publishedIn |
gptkb:Nature
gptkb:science gptkb:Genome_Research |
| gptkbp:regulates |
FDA (for clinical use)
|
| gptkbp:relatedTo |
gptkb:Affymetrix
gptkb:GeneChip RNA sequencing cDNA array oligonucleotide array |
| gptkbp:requires |
hybridization buffer
labeled nucleic acids scanning equipment washing steps |
| gptkbp:usedFor |
cancer research
pharmacogenomics genotyping gene expression profiling diagnosis of diseases mutation analysis SNP detection comparative genomic hybridization |
| gptkbp:usedIn |
personalized medicine
agricultural genomics toxicogenomics microbial detection |
| gptkbp:bfsParent |
gptkb:CMOS
|
| gptkbp:bfsLayer |
5
|