|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:approvedBy
|
1976
|
|
gptkbp:ATCCode
|
gptkb:C07AB03
|
|
gptkbp:bioavailability
|
50% (oral)
|
|
gptkbp:brand
|
gptkb:Atenololum
gptkb:Tenormin
Atenix
|
|
gptkbp:CASNumber
|
gptkb:29122-68-7
|
|
gptkbp:contraindication
|
asthma
heart block
severe bradycardia
|
|
gptkbp:eliminationHalfLife
|
6-7 hours
|
|
gptkbp:excretion
|
gptkb:kidney
|
|
gptkbp:genericAvailable
|
true
|
|
gptkbp:hasInChIKey
|
METKIMKYRPQLGS-UHFFFAOYSA-N
|
|
gptkbp:hasMolecularFormula
|
C14H22N2O3
|
|
gptkbp:hasSMILES
|
CC(C)NCC(COC1=CC=CC=C1C(=O)N)O
|
|
gptkbp:hasUNII
|
50VV3VW0TI
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
D00233
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:isBetaBlocker
|
true
|
|
gptkbp:IUPACName
|
4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
|
|
gptkbp:KEGGID
|
gptkb:D00233
|
|
gptkbp:legalStatus
|
Rx-only (US)
|
|
gptkbp:mechanismOfAction
|
selective beta-1 adrenergic receptor antagonist
|
|
gptkbp:meltingPoint
|
158-160°C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
266.34 g/mol
|
|
gptkbp:name
|
gptkb:Atenolol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:PubChem_CID
|
2162
DB00335
2249
2904
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
dizziness
fatigue
bradycardia
cold extremities
|
|
gptkbp:synonym
|
gptkb:Tenormin
|
|
gptkbp:usedFor
|
gptkb:arrhythmia
myocardial infarction
hypertension
angina pectoris
migraine prophylaxis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:buspirone
|
|
gptkbp:bfsLayer
|
7
|