|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:administeredBy
|
oral
topical
intravenous
|
|
gptkbp:ATCCode
|
J01BA01
|
|
gptkbp:availableOn
|
gptkb:hospital
capsule
suspension
injection
eye drops
|
|
gptkbp:bannedIn
|
United States (in food animals)
|
|
gptkbp:CASNumber
|
56-75-7
|
|
gptkbp:contraindication
|
newborns
|
|
gptkbp:discoveredIn
|
1947
|
|
gptkbp:eliminatedIn
|
renal
hepatic
|
|
gptkbp:halfLife
|
1.5-4 hours
|
|
gptkbp:hasMolecularFormula
|
C11H12Cl2N2O5
|
|
gptkbp:hasUNII
|
140QMO216E
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
D00222
|
|
gptkbp:isAntibiotic
|
true
|
|
gptkbp:isApprovedDrug
|
true
|
|
gptkbp:isNotUsedFor
|
minor infections
|
|
gptkbp:isUsedInVeterinaryMedicine
|
true
|
|
gptkbp:KEGGID
|
gptkb:D00222
|
|
gptkbp:legalStatus
|
Rx-only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit
|
|
gptkbp:meltingPoint
|
150-151°C
|
|
gptkbp:metabolism
|
liver (glucuronidation)
|
|
gptkbp:molecularWeight
|
323.13 g/mol
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:producedBy
|
chemical synthesis
fermentation
|
|
gptkbp:PubChem_CID
|
5959
17698
DB00446
|
|
gptkbp:riskFactor
|
serious toxicity
|
|
gptkbp:sideEffect
|
gptkb:gray_baby_syndrome
aplastic anemia
bone marrow suppression
|
|
gptkbp:synonym
|
gptkb:Chloramphenicolum
gptkb:Chloromycetin
|
|
gptkbp:usedFor
|
gptkb:rickettsial_infections
meningitis
typhoid fever
treatment of serious infections
|
|
gptkbp:wasOriginallyIsolatedFrom
|
gptkb:Streptomyces_venezuelae
|
|
gptkbp:bfsParent
|
gptkb:ChEMBL1044
gptkb:acyclovir
gptkb:CHEMBL1092
|
|
gptkbp:bfsLayer
|
6
|