|
gptkbp:instanceOf
|
gptkb:protein
biomarker
|
|
gptkbp:alternativeName
|
gptkb:CST3
gamma-trace
|
|
gptkbp:associatedWith
|
gptkb:Alzheimer's_disease
atherosclerosis
neurodegenerative diseases
cardiovascular risk
|
|
gptkbp:canBeFilteredBy
|
glomerulus
|
|
gptkbp:compatibleWith
|
gptkb:food
inflammation
muscle mass
|
|
gptkbp:degradedBy
|
proximal tubule
|
|
gptkbp:discoveredIn
|
1961
|
|
gptkbp:elevatedIn
|
renal dysfunction
thyroid dysfunction
|
|
gptkbp:encodedBy
|
gptkb:CST3_gene
|
|
gptkbp:expressedIn
|
gptkb:kidney
gptkb:placenta
gptkb:testis
brain
liver
pancreas
|
|
gptkbp:foundIn
|
human body
blood plasma
cerebrospinal fluid
|
|
gptkbp:function
|
cysteine protease inhibitor
|
|
gptkbp:halfLife
|
1.5 hours
|
|
gptkbp:HGNC_ID
|
2477
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cystatin C
|
|
gptkbp:locatedOnChromosome
|
chromosome 20p11.21
|
|
gptkbp:measures
|
immunoassay
nephelometry
turbidimetry
|
|
gptkbp:molecularWeight
|
13 kDa
|
|
gptkbp:OMIM
|
604312
|
|
gptkbp:PDB
|
3GAX
|
|
gptkbp:producedBy
|
all nucleated cells
|
|
gptkbp:range
|
0.6–1.0 mg/L (adults)
|
|
gptkbp:reabsorbedBy
|
proximal tubule
|
|
gptkbp:significance
|
marker for acute kidney injury
marker for chronic kidney disease
|
|
gptkbp:structure
|
single-chain polypeptide
|
|
gptkbp:UniProtID
|
P01034
|
|
gptkbp:usedFor
|
assessment of kidney function
estimation of glomerular filtration rate
|
|
gptkbp:usedIn
|
gptkb:CKD-EPI_equation
gptkb:MDRD_equation
pediatric GFR estimation
|
|
gptkbp:bfsParent
|
gptkb:Cystatin_G_protein
|
|
gptkbp:bfsLayer
|
7
|