Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
biomarker |
| gptkbp:alternativeName |
gptkb:CST3
Cystatin 3 gamma-trace |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
hereditary cerebral amyloid angiopathy |
| gptkbp:category |
gptkb:cystatin_superfamily
extracellular protein |
| gptkbp:degradedBy |
renal proximal tubule
|
| gptkbp:discoveredIn |
1961
|
| gptkbp:encodedBy |
gptkb:CST3_gene
|
| gptkbp:foundIn |
blood
cerebrospinal fluid saliva human body fluids |
| gptkbp:function |
cysteine protease inhibitor
|
| gptkbp:halfLife |
1.5 hours
|
| gptkbp:HGNC_ID |
2477
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cystatin-C
|
| gptkbp:inhibitedBy |
papain
cathepsins legumain |
| gptkbp:locatedOnChromosome |
chromosome 20p11.21
|
| gptkbp:measures |
immunoassay
|
| gptkbp:molecularWeight |
13 kDa
|
| gptkbp:OMIM |
604312
|
| gptkbp:PDB |
3GAX
|
| gptkbp:producedBy |
all nucleated cells
|
| gptkbp:range |
0.6–1.0 mg/L (adults)
|
| gptkbp:significance |
associated with cardiovascular risk
marker for acute kidney injury marker for chronic kidney disease |
| gptkbp:structure |
single-chain polypeptide
|
| gptkbp:UniProtID |
P01034
|
| gptkbp:usedFor |
assessment of kidney function
estimation of glomerular filtration rate |
| gptkbp:bfsParent |
gptkb:Cystatin_G
|
| gptkbp:bfsLayer |
7
|