Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
|
gptkbp:alsoKnownAs |
gptkb:Corey–House–Posner–Whitesides_reaction
|
gptkbp:application |
synthesis of complex organic molecules
|
gptkbp:category |
name reaction in organic chemistry
|
gptkbp:developedBy |
gptkb:George_Whitesides
gptkb:Elias_James_Corey gptkb:Herbert_O._House gptkb:Gary_Posner |
gptkbp:firstReported |
1972
|
https://www.w3.org/2000/01/rdf-schema#label |
Corey–House synthesis
|
gptkbp:involves |
alkyl halides
organocopper reagents |
gptkbp:limitation |
secondary and tertiary alkyl halides are less reactive
|
gptkbp:mechanismOfAction |
nucleophilic substitution
|
gptkbp:namedAfter |
gptkb:Elias_James_Corey
gptkb:Herbert_O._House |
gptkbp:product |
alkene
|
gptkbp:type |
coupling reaction
carbon–carbon bond formation |
gptkbp:uses |
lithium dialkylcuprate
primary alkyl halide |
gptkbp:bfsParent |
gptkb:Elias_J._Corey
|
gptkbp:bfsLayer |
5
|