Corey–House synthesis

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:alsoKnownAs gptkb:Corey–House–Posner–Whitesides_reaction
gptkbp:application synthesis of complex organic molecules
gptkbp:category name reaction in organic chemistry
gptkbp:developedBy gptkb:George_Whitesides
gptkb:Elias_James_Corey
gptkb:Herbert_O._House
gptkb:Gary_Posner
gptkbp:firstReported 1972
https://www.w3.org/2000/01/rdf-schema#label Corey–House synthesis
gptkbp:involves alkyl halides
organocopper reagents
gptkbp:limitation secondary and tertiary alkyl halides are less reactive
gptkbp:mechanismOfAction nucleophilic substitution
gptkbp:namedAfter gptkb:Elias_James_Corey
gptkb:Herbert_O._House
gptkbp:product alkene
gptkbp:type coupling reaction
carbon–carbon bond formation
gptkbp:uses lithium dialkylcuprate
primary alkyl halide
gptkbp:bfsParent gptkb:Elias_J._Corey
gptkbp:bfsLayer 5