|
gptkbp:instanceOf
|
gptkb:Corticosteroid
Topical medication
|
|
gptkbp:ATCCode
|
D07AD01
|
|
gptkbp:brand
|
Clobex
Dermovate
Olux
Temovate
|
|
gptkbp:CASNumber
|
25122-46-7
|
|
gptkbp:chemicalFormula
|
C25H32ClFO5
|
|
gptkbp:contraindication
|
gptkb:Rosacea
Acne
Perioral dermatitis
Viral skin infections
|
|
gptkbp:discoveredBy
|
GlaxoSmithKline
|
|
gptkbp:drugClass
|
gptkb:Corticosteroid
|
|
gptkbp:eliminationHalfLife
|
8 hours
|
|
gptkbp:form
|
gptkb:Cream
gptkb:shampoo
Foam
Gel
Spray
Ointment
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Clobetasol propionate
|
|
gptkbp:introducedIn
|
1978
|
|
gptkbp:legalStatus
|
Prescription only
|
|
gptkbp:mechanismOfAction
|
Glucocorticoid receptor agonist
|
|
gptkbp:metabolism
|
Hepatic
|
|
gptkbp:molecularWeight
|
466.97 g/mol
|
|
gptkbp:notRecommendedFor
|
Children under 12 (without medical supervision)
|
|
gptkbp:potency
|
Very high
|
|
gptkbp:pregnancyCategory
|
gptkb:C_(Australia)
C (US)
|
|
gptkbp:prescriptionStatus
|
Rx only
|
|
gptkbp:riskFactor
|
Adrenal suppression (if overused)
|
|
gptkbp:routeOfAdministration
|
Topical
|
|
gptkbp:sideEffect
|
gptkb:Contact_dermatitis
Irritation
Burning sensation
Skin thinning
Stretch marks
Systemic absorption (rare)
|
|
gptkbp:storage
|
Room temperature
|
|
gptkbp:usedFor
|
Eczema
Psoriasis
Dermatitis
Lichen planus
Autoimmune skin disorders
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
Yes
|
|
gptkbp:bfsParent
|
gptkb:Taro_Pharmaceutical_Industries
|
|
gptkbp:bfsLayer
|
7
|