Statements (59)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Medication
|
| gptkbp:activeDuring |
Spironolactone
|
| gptkbp:administrativeDivision |
Once daily
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:availability |
Prescription only
|
| gptkbp:clinicalTrials |
Phase 3
Long-term management AHA/ACC guidelines NCT03412345 |
| gptkbp:colors |
Clear
|
| gptkbp:compatibleWith |
Variable
|
| gptkbp:contraindication |
gptkb:Addison's_disease
Diarrhea Headache Rash Hypotension Renal impairment Anuria |
| gptkbp:dosageForm |
Liquid
|
| gptkbp:drugInterdiction |
Diuretics
Caution with diuretics Potassium-sparing diuretics |
| gptkbp:endOfLife |
13 hours
|
| gptkbp:firstAppearance |
2019-09-30
|
| gptkbp:flavorProfile |
Cherry
|
| gptkbp:formulation |
Suspension
Oral suspension |
| gptkbp:gestationPeriod |
C
|
| gptkbp:hasPopulation |
Adults
Pediatric patients |
| gptkbp:healthcare |
Take with food
Important for efficacy |
| gptkbp:historical_analysis |
Efficacy in heart failure
|
| https://www.w3.org/2000/01/rdf-schema#label |
Carospir
|
| gptkbp:interactsWith |
NSAIDs
ACE inhibitors Potassium supplements |
| gptkbp:is_monitored_by |
Blood pressure
Electrolytes Renal function |
| gptkbp:label |
Prescription only
|
| gptkbp:mandates |
Edema
Heart failure |
| gptkbp:manufacturer |
gptkb:Amgen
|
| gptkbp:nutritionalValue |
Liver
|
| gptkbp:offers |
Varies by pharmacy
|
| gptkbp:packaging |
Bottle
|
| gptkbp:route |
Oral
|
| gptkbp:safetyFeatures |
Monitor potassium levels
|
| gptkbp:sells |
gptkb:Carospir
|
| gptkbp:sideEffect |
Dizziness
Fatigue Nausea Hyperkalemia |
| gptkbp:skills |
100 mg/5 mL
|
| gptkbp:storage |
Room temperature
|
| gptkbp:triggerType |
Aldosterone_antagonist
|
| gptkbp:usedFor |
Hypertension
|
| gptkbp:waterManagement |
Urine
|