COVID-19 mRNA vaccines

GPTKB entity

Statements (49)
Predicate Object
gptkbp:instanceOf vaccine
gptkbp:administeredBy intramuscular injection
gptkbp:approvedBy gptkb:WHO
gptkb:FDA
gptkb:EMA
2020
gptkbp:boosterRecommended yes
gptkbp:boosters yes
bivalent
monovalent
gptkbp:brand gptkb:Comirnaty
gptkb:Spikevax
gptkbp:clinicalTrialPhase Phase 3 completed
gptkbp:contains messenger RNA
gptkbp:developedBy gptkb:Moderna
gptkb:Pfizer-BioNTech
gptkbp:duration wanes over time
gptkbp:effect high against severe disease
reduced against some variants
gptkbp:eligiblePopulation adults
children (age varies by country)
gptkbp:emergencyServices granted in many countries
gptkbp:excludes adjuvant
live virus
preservative
gptkbp:globalPresence widespread
https://www.w3.org/2000/01/rdf-schema#label COVID-19 mRNA vaccines
gptkbp:notRecommendedFor severe allergic reaction to vaccine ingredients
gptkbp:pregnancyCategory generally considered safe
gptkbp:regulates emergency use in others
full approval in some countries
gptkbp:requires two doses (primary series)
gptkbp:sideEffect fever
fatigue
headache
muscle pain
anaphylaxis
chills
myocarditis
injection site pain
gptkbp:storage gptkb:frozen_(Moderna)
gptkb:ultra-cold_(Pfizer-BioNTech)
gptkbp:target gptkb:SARS-CoV-2_spike_protein
gptkbp:technology lipid nanoparticle delivery
gptkbp:updatedForVariants yes
gptkbp:usedFor prevention of COVID-19
gptkbp:WHOModelListOfEssentialMedicines included
gptkbp:bfsParent gptkb:Katalin_Karikó
gptkbp:bfsLayer 5