Statements (25)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:chemical_compound
|
gptkbp:hasAssay |
gptkb:human
gptkb:Binding |
gptkbp:hasAssayDescription |
Inhibition of GSK-3 beta activity in vitro
|
gptkbp:hasBiologicalActivity |
inhibitor
|
gptkbp:hasHBA |
6
|
gptkbp:hasHBD |
2
|
gptkbp:hasInChIKey |
QZJQJQJQJQJQJQ-UHFFFAOYSA-N
|
gptkbp:hasLogP |
2.2
|
gptkbp:hasMolecularFormula |
C17H19N3O3S
|
gptkbp:hasRotatableBonds |
6
|
gptkbp:hasSMILES |
COc1ccc(NC(=O)S(=O)(=O)c2ccc(NC)c([N+](=O)[O-])c2)cc1
|
gptkbp:hasStandardType |
IC50
|
gptkbp:hasStandardValue |
0.013 μM
|
gptkbp:hasTPSA |
120.2
|
https://www.w3.org/2000/01/rdf-schema#label |
CHEMBL1201563
|
gptkbp:molecularWeight |
345.42
|
gptkbp:PubChem_CID |
gptkb:CHEMBL1201563
10199353 8366672 |
gptkbp:synonym |
gptkb:GSK-3_inhibitor_VIII
N-(4-methoxyphenyl)-4-(methylamino)-3-nitrobenzenesulfonamide |
gptkbp:target |
gptkb:Glycogen_synthase_kinase-3_beta
|
gptkbp:bfsParent |
gptkb:Proleukin
|
gptkbp:bfsLayer |
6
|