Statements (40)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
CUGBP, Elav-like family proteins
|
| gptkbp:contains |
RNA recognition motif
|
| gptkbp:discoveredBy |
studies of CUG-binding proteins
|
| gptkbp:domain |
divergent linker domain
three RNA recognition motifs (RRMs) |
| gptkbp:expressedIn |
gptkb:skeletal_muscle
gptkb:testis brain tissue heart tissue |
| gptkbp:foundIn |
invertebrates
vertebrates |
| gptkbp:function |
RNA binding
regulation of mRNA translation regulation of alternative splicing regulation of mRNA stability |
| https://www.w3.org/2000/01/rdf-schema#label |
CELF proteins
|
| gptkbp:involves |
gptkb:myotonic_dystrophy
neurological disorders |
| gptkbp:member |
gptkb:CELF1
gptkb:CELF2 CELF3 CELF4 CELF5 CELF6 |
| gptkbp:mutationAssociatedWith |
neurological symptoms
muscle dysfunction splicing misregulation |
| gptkbp:orthologIn |
gptkb:Caenorhabditis_elegans
gptkb:Drosophila_melanogaster |
| gptkbp:proteinFamily |
CELF gene family
|
| gptkbp:regulates |
translator
polyadenylation mRNA decay pre-mRNA alternative splicing muscle-specific splicing events neuronal-specific splicing events |
| gptkbp:relatedTo |
Elav-like proteins
|
| gptkbp:bfsParent |
gptkb:RRM_domain
|
| gptkbp:bfsLayer |
7
|