Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
Cerebral Cavernous Malformation signaling complex
|
gptkbp:associatedWith |
cerebral cavernous malformations
CCM1 CCM2 CCM3 cerebral cavernous malformation disease |
gptkbp:composedOf |
gptkb:KRIT1
CCM2 PDCD10 |
gptkbp:discoveredIn |
2000s
|
gptkbp:function |
regulation of endothelial cell junctions
maintenance of vascular integrity |
https://www.w3.org/2000/01/rdf-schema#label |
CCM signaling complex
|
gptkbp:interactsWith |
gptkb:RhoA_GTPase
ICAP1 |
gptkbp:locale |
endothelial cells
|
gptkbp:mutationAssociatedWith |
vascular malformations
|
gptkbp:regulates |
angiogenesis
cytoskeletal organization cell-cell adhesion |
gptkbp:bfsParent |
gptkb:Cerebral_Cavernous_Malformation_Protein
|
gptkbp:bfsLayer |
7
|