Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alternativeName |
gptkb:SCPA
gptkb:ScpA |
| gptkbp:biologicalProcess |
gptkb:serine_protease
|
| gptkbp:cleavage_site |
C-terminal of C5a
|
| gptkbp:EC_number |
3.4.21.110
|
| gptkbp:foundIn |
gptkb:Streptococcus_pyogenes
gptkb:Streptococcus_agalactiae |
| gptkbp:function |
cleaves human complement component C5a
|
| gptkbp:gene |
gptkb:scpA
|
| gptkbp:GO_term |
GO:0004252
|
| https://www.w3.org/2000/01/rdf-schema#label |
C5a peptidase
|
| gptkbp:inhibitedBy |
complement-mediated immune response
|
| gptkbp:location |
cell surface
|
| gptkbp:molecularWeight |
~120 kDa
|
| gptkbp:pathogen_virulence_factor |
yes
|
| gptkbp:proteinFamily |
gptkb:PF03761
|
| gptkbp:role_in_pathogenesis |
inhibits neutrophil recruitment
|
| gptkbp:structure |
multi-domain protein
|
| gptkbp:substrate |
gptkb:C5a_chemotaxin
|
| gptkbp:UniProtID |
P0C0P6
|
| gptkbp:bfsParent |
gptkb:Streptococcus_pyogenes
|
| gptkbp:bfsLayer |
6
|