Statements (68)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:bfsLayer |
4
|
| gptkbp:bfsParent |
gptkb:B-cell_ALL
|
| gptkbp:affects |
B cells
|
| gptkbp:associated_with |
gptkb:fandom
thrombocytopenia infection risk lymphadenopathy painful lymph nodes hepatomegaly splenomegaly abdominal mass leukopenia hyperuricemia EBV infection tumor lysis syndrome bone marrow infiltration central nervous system involvement gastrointestinal involvement jaw lesions orbital involvement skin involvement testicular involvement |
| gptkbp:caused_by |
chromosomal translocation
|
| gptkbp:clinical_trial |
ongoing research
cytogenetic abnormalities high proliferation index extramedullary disease |
| gptkbp:first_described_by |
1950s
|
| gptkbp:genetic_diversity |
T P53 gene
BC L6 gene MYC gene |
| https://www.w3.org/2000/01/rdf-schema#label |
Burkitt leukemia
|
| gptkbp:is_characterized_by |
rapid tumor growth
|
| gptkbp:is_often_used_in |
gptkb:Africa
gptkb:Person gptkb:New_Guinea |
| gptkbp:named_after |
Dr. Denis Burkitt
|
| gptkbp:risk_factor |
malaria
immunosuppression HIV infection |
| gptkbp:social_responsibility |
blood tests
imaging studies more common in males biopsy depends on stage at diagnosis good with treatment depends on response to treatment can be curable higher incidence in equatorial Africa rare in adults |
| gptkbp:symptoms |
weight loss
abdominal pain fever night sweats swollen lymph nodes |
| gptkbp:treatment |
gptkb:vaccine
radiation therapy chemotherapy targeted therapy stem cell transplant maintenance therapy CNS prophylaxis intensive chemotherapy regimens |
| gptkbp:type_of |
gptkb:non-Hodgkin_lymphoma
endemic Burkitt lymphoma immunodeficiency-associated Burkitt lymphoma sporadic Burkitt lymphoma |