|
gptkbp:instanceOf
|
gptkb:recreational_drug
gptkb:benzodiazepine
|
|
gptkbp:ATCCode
|
N05BA08
|
|
gptkbp:brand
|
Lectopam
Lexotan
Lexotanil
|
|
gptkbp:CASNumber
|
1812-30-2
|
|
gptkbp:category
|
gptkb:sedative
gptkb:muscle_relaxant
gptkb:hypnotic
GABAA receptor positive allosteric modulator
|
|
gptkbp:chemicalFormula
|
C14H10BrN3O
|
|
gptkbp:color
|
white to off-white
|
|
gptkbp:contraindication
|
gptkb:myasthenia_gravis
severe respiratory insufficiency
sleep apnea syndrome
severe hepatic insufficiency
|
|
gptkbp:discoveredBy
|
gptkb:Roche
|
|
gptkbp:eliminationHalfLife
|
10-20 hours
|
|
gptkbp:excretion
|
renal
|
|
gptkbp:indication
|
anxiety disorders
short-term relief of severe anxiety
|
|
gptkbp:introducedIn
|
1963
|
|
gptkbp:IUPACName
|
7-bromo-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
positive allosteric modulator of GABA-A receptor
|
|
gptkbp:meltingPoint
|
237–238 °C
|
|
gptkbp:metabolism
|
hepatic
|
|
gptkbp:pregnancyCategory
|
gptkb:D_(Australia)
D (US)
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1082
2348
2442
|
|
gptkbp:riskFactor
|
dependence
abuse potential
withdrawal symptoms
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
muscle relaxation
drowsiness
sedation
ataxia
impaired coordination
memory impairment
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:synonym
|
Bromazepamum
Bromazepan
|
|
gptkbp:UNII
|
5MG3P0FD8H
|
|
gptkbp:bfsParent
|
gptkb:N05BA
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Bromazepam
|