Statements (53)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | gptkb:mental_disorder | 
| gptkbp:affects | adolescents adults children (rarely) | 
| gptkbp:alsoKnownAs | bipolar disorder manic-depressive illness | 
| gptkbp:canBeManagedBy | long-term treatment | 
| gptkbp:cause | occupational difficulties impaired social functioning increased risk of suicide | 
| gptkbp:characterizedBy | episodes of depression episodes of mania | 
| gptkbp:comorbidity | ADHD eating disorders substance use disorders anxiety disorders | 
| gptkbp:diagnosedBy | psychiatric evaluation | 
| gptkbp:DSM-5_code | 296.x | 
| gptkbp:firstDescribed | gptkb:Emil_Kraepelin | 
| gptkbp:hasBiologicalBasis | neurotransmitter imbalance brain structure abnormalities | 
| gptkbp:hasGeneticComponent | yes | 
| gptkbp:ICD-10_code | gptkb:F31 | 
| gptkbp:offersCourse | episodic chronic | 
| gptkbp:onset | usually late adolescence or early adulthood | 
| gptkbp:prevalence | about 1% of the population | 
| gptkbp:prognosis | variable | 
| gptkbp:riskFactor | gptkb:substance_abuse family history of bipolar disorder high stress | 
| gptkbp:subspecies | gptkb:Bipolar_II_disorder gptkb:Bipolar_I_disorder gptkb:Cyclothymic_disorder | 
| gptkbp:symptom | mood swings fatigue suicidal thoughts irritability decreased need for sleep elevated mood feelings of sadness increased activity loss of interest | 
| gptkbp:treatment | gptkb:psychotherapy antipsychotic medications mood stabilizers antidepressants | 
| gptkbp:triggeredBy | substance use sleep deprivation stressful life events | 
| gptkbp:bfsParent | gptkb:F31 | 
| gptkbp:bfsLayer | 8 | 
| https://www.w3.org/2000/01/rdf-schema#label | Bipolar affective disorder |