BioSAXS

GPTKB entity

Statements (55)
Predicate Object
gptkbp:instanceOf analytical technique
gptkbp:advantage no need for crystallization
samples in near-native conditions
gptkbp:analyzes conformational changes
shape of macromolecules
oligomeric state
size of macromolecules
gptkbp:database gptkb:PDB
gptkb:SASBDB
gptkbp:developedBy 1970s
gptkbp:facilityId synchrotron facility
laboratory X-ray source
gptkbp:fullName gptkb:Biological_Small-Angle_X-ray_Scattering
https://www.w3.org/2000/01/rdf-schema#label BioSAXS
gptkbp:limitation low resolution
requires monodisperse samples
sensitive to aggregation
gptkbp:measures scattering intensity as a function of angle
gptkbp:notableInstitution gptkb:SOLEIL
gptkb:EMBL_Hamburg
gptkb:Diamond_Light_Source
gptkb:ESRF
gptkbp:provides low-resolution structural information
gptkbp:relatedTo gptkb:SAXS
gptkb:cryo-EM
X-ray crystallography
NMR spectroscopy
gptkbp:resolution 1-2 nm
gptkbp:sampleState gptkb:government_agency
gptkbp:software gptkb:ATSAS
gptkb:BioXTAS_RAW
gptkb:CRYSOL
gptkb:DAMMIF
gptkb:DAMMIN
gptkb:FoXS
gptkb:GNOM
gptkb:PRIMUS
gptkbp:type nucleic acids
proteins
viruses
membrane proteins
complexes
nanodiscs
pair distance distribution functions
scattering curves
gptkbp:usedFor analyzing complexes of biomolecules
analyzing nucleic acid structure
analyzing protein structure
studying biological macromolecules in solution
gptkbp:usedIn biochemistry
biophysics
structural biology
gptkbp:uses X-ray scattering
gptkbp:bfsParent gptkb:Cornell_High_Energy_Synchrotron_Source
gptkbp:bfsLayer 6