Bicycle Toxin Conjugates (BTCs)
GPTKB entity
Statements (15)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
antibody-drug conjugate alternative |
| gptkbp:advantage |
potential for better tumor penetration
smaller size than antibodies |
| gptkbp:clinicalTrialPhase |
ongoing
|
| gptkbp:developedBy |
gptkb:Bicycle_Therapeutics
|
| gptkbp:example |
gptkb:BT5528
gptkb:BT8009 |
| https://www.w3.org/2000/01/rdf-schema#label |
Bicycle Toxin Conjugates (BTCs)
|
| gptkbp:mechanismOfAction |
targeted delivery of cytotoxins
|
| gptkbp:structure |
bicyclic peptide linked to cytotoxic payload
|
| gptkbp:target |
tumor-associated antigens
|
| gptkbp:usedFor |
gptkb:cancer
|
| gptkbp:bfsParent |
gptkb:Bicycle_Therapeutics
|
| gptkbp:bfsLayer |
6
|