Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:brand |
gptkb:Berinert
|
| gptkbp:clinical_trial |
Phase III trials
safety and efficacy studies long-term management emergency treatment investigating long-term effects |
| gptkbp:competitors |
other C1 inhibitors
|
| gptkbp:contraindication |
hypersensitivity to C1 esterase inhibitor
|
| gptkbp:dosage_form |
injection
|
| gptkbp:education |
important for effective use
|
| gptkbp:educational_programs |
provided to patients
|
| gptkbp:effective_date |
2009-10-30
|
| gptkbp:formulation |
lyophilized powder for reconstitution
|
| gptkbp:frequency |
as needed for attacks
regular intervals for prophylaxis |
| gptkbp:healthcare |
injectable solution
|
| https://www.w3.org/2000/01/rdf-schema#label |
Berinert
|
| gptkbp:indication |
acute treatment of angioedema attacks
prophylaxis of angioedema attacks |
| gptkbp:ingredients |
gptkb:C1_esterase_inhibitor
|
| gptkbp:interacts_with |
limited interactions known
|
| gptkbp:is_monitored_by |
required for adverse effects
|
| gptkbp:is_used_for |
treatment of hereditary angioedema
|
| gptkbp:manager |
intravenous
|
| gptkbp:manufacturer |
gptkb:CSL_Behring
|
| gptkbp:marketed_as |
gptkb:legislation
gptkb:United_States gptkb:Native_American_tribe |
| gptkbp:packaging |
single-use vial
|
| gptkbp:pharmacokinetics |
increases C1 inhibitor levels
half-life of approximately 60 hours |
| gptkbp:population |
gptkb:Person
adults |
| gptkbp:previous_name |
gptkb:C1_esterase_inhibitor
|
| gptkbp:price |
varies by region
|
| gptkbp:provides_information_on |
recommended for hereditary angioedema
|
| gptkbp:regulatory_compliance |
FDA approved
EMA approved |
| gptkbp:requires |
available online
|
| gptkbp:research |
ongoing studies for new indications
|
| gptkbp:safety_features |
generally well tolerated
|
| gptkbp:scholarships |
gptkb:stock_market_index
|
| gptkbp:side_effect |
fatigue
headache nausea fever urticaria thromboembolic events anaphylaxis |
| gptkbp:storage |
refrigerated
|
| gptkbp:supply_chain |
cold chain required
|
| gptkbp:treatment |
improvement in quality of life
reduction in attack frequency |
| gptkbp:bfsParent |
gptkb:Cinryze
|
| gptkbp:bfsLayer |
5
|