Statements (55)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
alkaloid |
| gptkbp:ATCCode |
A07AX16
|
| gptkbp:biosynthesized_from |
gptkb:tyrosine
dopamine 4-hydroxyphenylacetaldehyde |
| gptkbp:CASNumber |
2086-83-1
|
| gptkbp:chemicalFormula |
C20H18NO4
|
| gptkbp:color |
yellow
|
| gptkbp:contraindication |
pregnancy
neonates breastfeeding |
| gptkbp:drugClass |
antioxidant
anti-inflammatory antifungal antiviral antidiarrheal antimicrobial antidiabetic antihypertensive antiprotozoal cholesterol-lowering |
| gptkbp:drugInteraction |
immunosuppressants
anticoagulants antidiabetic drugs CYP3A4 substrates |
| gptkbp:foundIn |
gptkb:Berberis_vulgaris
Phellodendron amurense Coptis chinensis Hydrastis canadensis |
| gptkbp:hasHistoryOfUse |
gptkb:traditional_medicine
gptkb:Ayurveda |
| gptkbp:hasInChIKey |
RGUNRWZAIYLSKJ-IBOSZNHHSA-O
|
| gptkbp:hasSMILES |
COC1=CC2=C(C=C1)N3CC4=CC(=C(C=C4C3=C2)OC)OC
|
| gptkbp:hasUNII |
Z8NYA835TV
|
| https://www.w3.org/2000/01/rdf-schema#label |
Berberine
|
| gptkbp:isIsoquinolineAlkaloid |
true
|
| gptkbp:isQuaternaryAmmonium |
true
|
| gptkbp:IUPACName |
(R)-2,3-methylenedioxy-9,10-dimethoxy-5,6-dihydroisoquinolino[3,2-a]isoquinolinium
|
| gptkbp:meltingPoint |
145 °C
|
| gptkbp:molecularWeight |
336.37 g/mol
|
| gptkbp:PubChem_CID |
2353
CHEBI:16386 |
| gptkbp:sideEffect |
nausea
constipation headache gastrointestinal upset |
| gptkbp:solubility |
poorly soluble in water
soluble in alcohol |
| gptkbp:usedAs |
gptkb:traditional_medicine
dye |
| gptkbp:bfsParent |
gptkb:Greater_celandine
gptkb:Barberry gptkb:Huanglian |
| gptkbp:bfsLayer |
8
|