Bacterial Artificial Chromosome

URI: https://gptkb.org/entity/Bacterial_Artificial_Chromosome
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:cloning_vector
gptkbp:abbreviation gptkb:BAC
gptkbp:advantage low recombination frequency
stable propagation of large DNA fragments
gptkbp:canBeMaintainedAs single copy in E. coli
gptkbp:canCarryInsertSize 100-300 kilobases
gptkbp:component selectable marker
cloning site
origin of replication
par genes
gptkbp:derivedFrom gptkb:F-plasmid
gptkbp:developedBy 1987
gptkbp:inventedBy gptkb:Shizuya_Hiroaki
gptkb:Melvin_Simon
gptkbp:organism gptkb:Bacteria
gptkbp:relatedTo gptkb:P1-derived_Artificial_Chromosome
gptkb:Yeast_Artificial_Chromosome
gptkbp:selectableMarker gptkb:antibiotic_resistance_gene
gptkbp:usedFor comparative genomics
gene therapy research
disease gene identification
functional studies of genes
mapping and analysis of complex genomes
physical mapping
transgenic animal production
gptkbp:usedIn gptkb:Human_Genome_Project
genetic engineering
genome sequencing
functional genomics
gptkbp:bfsParent gptkb:BAC
gptkbp:bfsLayer 6
https://www.w3.org/2000/01/rdf-schema#label Bacterial Artificial Chromosome