|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:affiliatedWith
|
azalide
|
|
gptkbp:approvedBy
|
gptkb:United_States
gptkb:FDA
1991
|
|
gptkbp:ATCCode
|
gptkb:J01FA10
|
|
gptkbp:bioavailability
|
37%
|
|
gptkbp:brand
|
gptkb:Zithromax
gptkb:Zmax
|
|
gptkbp:CASNumber
|
83905-01-5
|
|
gptkbp:chemicalFormula
|
C38H72N2O12
|
|
gptkbp:contraindication
|
gptkb:liver_disease
allergy to macrolides
|
|
gptkbp:developedBy
|
gptkb:Croatia
|
|
gptkbp:discoveredBy
|
gptkb:Pliva
|
|
gptkbp:discoveredIn
|
1980
|
|
gptkbp:eliminationHalfLife
|
68 hours
|
|
gptkbp:excretion
|
urine
bile
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Azithromycin
|
|
gptkbp:KEGGID
|
D07452
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial protein synthesis
|
|
gptkbp:MedlinePlusID
|
a697037
|
|
gptkbp:MeSH_ID
|
D015242
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
748.984 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:proteinBinding
|
7–51%
|
|
gptkbp:PubChem_CID
|
447043
CHEBI:2955
DB00207
|
|
gptkbp:routeOfAdministration
|
oral
intravenous
|
|
gptkbp:sideEffect
|
nausea
vomiting
diarrhea
abdominal pain
allergic reaction
QT prolongation
|
|
gptkbp:target
|
50S ribosomal subunit
|
|
gptkbp:UNII
|
J2KLZ20U1M
|
|
gptkbp:usedFor
|
gptkb:sinusitis
gptkb:pneumonia
bronchitis
skin infections
ear infections
sexually transmitted infections
tonsillitis
chlamydia
gonorrhea
bacterial infections
respiratory tract infections
pharyngitis
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:Typhoid_Fever
|
|
gptkbp:bfsLayer
|
5
|