Array CGH

GPTKB entity

Statements (28)
Predicate Object
gptkbp:instanceOf genomic technique
gptkbp:alternativeTo gptkb:FISH
karyotyping
gptkbp:analyzes relative DNA copy number
gptkbp:compatibleWith inversions
balanced translocations
gptkbp:detects deletions
duplications
gptkbp:developedBy 1990s
gptkbp:fullName Array Comparative Genomic Hybridization
https://www.w3.org/2000/01/rdf-schema#label Array CGH
gptkbp:limitation cannot detect point mutations
cannot detect balanced rearrangements
gptkbp:output log2 ratio plots
gptkbp:relatedTo next-generation sequencing
SNP array
gptkbp:replacedBy conventional CGH
gptkbp:requires reference DNA
test DNA
gptkbp:resolution higher than conventional CGH
gptkbp:type genomic DNA
gptkbp:usedFor genome-wide screening
detecting copy number variations
gptkbp:usedIn cancer research
clinical diagnostics
gptkbp:uses gptkb:DNA_microarrays
gptkbp:bfsParent gptkb:Comparative_Genomic_Hybridization
gptkbp:bfsLayer 8