|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:drug
|
|
gptkbp:ATCCode
|
N04BC07
|
|
gptkbp:brand
|
Apokyn
Kynmobi
Movapo
|
|
gptkbp:CASNumber
|
58-00-4
|
|
gptkbp:category
|
gptkb:catecholamine
gptkb:emetic
gptkb:secondary_alcohol
gptkb:antiparkinsonian_agent
gptkb:naphthalene_derivative
dopaminergic agent
phenanthrene alkaloid
|
|
gptkbp:chemicalFormula
|
C17H17NO2
|
|
gptkbp:contraindication
|
concurrent use with 5HT3 antagonists
hypersensitivity to apomorphine
|
|
gptkbp:discoveredBy
|
Matthiessen and Wright
|
|
gptkbp:discoveredIn
|
1869
|
|
gptkbp:eliminationHalfLife
|
30-60 minutes
|
|
gptkbp:has_stereochemistry
|
R-enantiomer
|
|
gptkbp:IUPACName
|
(R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
|
|
gptkbp:KEGGID
|
D02913
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
gptkb:dopamine_agonist
|
|
gptkbp:meltingPoint
|
250 °C
|
|
gptkbp:MeSH_ID
|
D001059
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
267.32 g/mol
|
|
gptkbp:not_an_opioid
|
true
|
|
gptkbp:origin
|
derived from morphine
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:PubChem_CID
|
6005
CHEMBL1201207
DB01118
|
|
gptkbp:routeOfAdministration
|
sublingual
subcutaneous injection
|
|
gptkbp:sideEffect
|
nausea
vomiting
drowsiness
hypotension
hallucinations
|
|
gptkbp:solubility
|
slightly soluble in water
|
|
gptkbp:UNII
|
19D0HM3301
|
|
gptkbp:used_in_veterinary_medicine
|
emetic in dogs
|
|
gptkbp:usedFor
|
gptkb:Parkinson's_disease
erectile dysfunction
|
|
gptkbp:bfsParent
|
gptkb:N04BB
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Apomorphine
|