Statements (50)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
gptkb:drug |
| gptkbp:ATCCode |
N04BC07
|
| gptkbp:brand |
Apokyn
Kynmobi Movapo |
| gptkbp:CASNumber |
58-00-4
|
| gptkbp:category |
antiparkinsonian agent
dopaminergic agent secondary alcohol catecholamine naphthalene derivative emetic phenanthrene alkaloid |
| gptkbp:chemicalFormula |
C17H17NO2
|
| gptkbp:contraindication |
concurrent use with 5HT3 antagonists
hypersensitivity to apomorphine |
| gptkbp:discoveredBy |
Matthiessen and Wright
|
| gptkbp:discoveredIn |
1869
|
| gptkbp:eliminationHalfLife |
30-60 minutes
|
| gptkbp:has_stereochemistry |
R-enantiomer
|
| https://www.w3.org/2000/01/rdf-schema#label |
Apomorphine
|
| gptkbp:IUPACName |
(R)-5,6,6a,7-tetrahydro-6-methyl-4H-dibenzo[de,g]quinoline-10,11-diol
|
| gptkbp:KEGGID |
D02913
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
dopamine agonist
|
| gptkbp:meltingPoint |
250 °C
|
| gptkbp:MeSH_ID |
D001059
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
267.32 g/mol
|
| gptkbp:not_an_opioid |
true
|
| gptkbp:origin |
derived from morphine
|
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:PubChem_CID |
6005
CHEMBL1201207 DB01118 |
| gptkbp:routeOfAdministration |
sublingual
subcutaneous injection |
| gptkbp:sideEffect |
nausea
vomiting drowsiness hypotension hallucinations |
| gptkbp:solubility |
slightly soluble in water
|
| gptkbp:UNII |
19D0HM3301
|
| gptkbp:used_in_veterinary_medicine |
emetic in dogs
|
| gptkbp:usedFor |
gptkb:Parkinson's_disease
erectile dysfunction |
| gptkbp:bfsParent |
gptkb:N04BB
|
| gptkbp:bfsLayer |
8
|