|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:ATCCode
|
gptkb:J01CA01
|
|
gptkbp:CASNumber
|
gptkb:69-53-4
|
|
gptkbp:category
|
gptkb:drug
essential medicine
antibacterial drug
|
|
gptkbp:chemicalFormula
|
gptkb:C16H19N3O4S
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:developedBy
|
gptkb:United_Kingdom
|
|
gptkbp:discoveredBy
|
gptkb:Beecham_Group
|
|
gptkbp:eliminationHalfLife
|
1-1.5 hours
|
|
gptkbp:excretion
|
renal
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Ampicillin
|
|
gptkbp:introducedIn
|
1961
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:meltingPoint
|
>200°C (decomposes)
|
|
gptkbp:metabolism
|
minimal
|
|
gptkbp:molecularWeight
|
349.4 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
|
|
gptkbp:PubChem_CID
|
gptkb:DB00415
6249
|
|
gptkbp:resistantTo
|
beta-lactamase producing bacteria
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
allergic reaction
rash
|
|
gptkbp:solubility
|
water soluble
|
|
gptkbp:spectrumOfActivity
|
broad-spectrum
|
|
gptkbp:synonym
|
D-(-)-α-Aminobenzylpenicillin
Penbritin
Polyflex
|
|
gptkbp:UNII
|
7C5697DR9X
|
|
gptkbp:usedFor
|
meningitis
endocarditis
urinary tract infections
bacterial infections
gastrointestinal infections
respiratory tract infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:J01CA01
gptkb:Hindustan_Antibiotics
gptkb:Hindustan_Antibiotics_Limited
|
|
gptkbp:bfsLayer
|
7
|