Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:activities |
Bronchodilator
Phosphodiesterase inhibitor |
| gptkbp:approves |
gptkb:FDA
1950s |
| gptkbp:brand |
Aminophylline Injection
Aminophylline Oral Phyllocontin |
| gptkbp:category |
Bronchodilator
Respiratory agent |
| gptkbp:class |
Xanthine derivative
|
| gptkbp:clinical_trial |
Phase IV
|
| gptkbp:contraindication |
Peptic ulcer disease
Hyperthyroidism Seizure disorders |
| gptkbp:dissolved |
Water soluble
|
| gptkbp:dosage_form |
200 mg to 300 mg every 8 hours
400 mg to 600 mg daily |
| https://www.w3.org/2000/01/rdf-schema#label |
Aminophylline
|
| gptkbp:ingredients |
C7 H8 N4 O2
|
| gptkbp:interacts_with |
gptkb:Rifampin
gptkb:Ciprofloxacin Alcohol Erythromycin |
| gptkbp:is_available_on |
gptkb:product
gptkb:tablet Injection |
| gptkbp:is_used_for |
Asthma
Chronic obstructive pulmonary disease Bronchospasm |
| gptkbp:level |
8.6
6.0 to 7.0 |
| gptkbp:lifespan |
3 to 8 hours
|
| gptkbp:manager |
Intravenous
Oral |
| gptkbp:metabolism |
Liver
|
| gptkbp:side_effect |
gptkb:Tachycardia
gptkb:Anxiety gptkb:Insomnia gptkb:Nausea Dizziness Headache Cardiac arrhythmias Palpitations Hypotension Gastrointestinal upset |
| gptkbp:storage |
Room temperature
Protect from light |
| gptkbp:type_of |
317-34-0
|
| gptkbp:bfsParent |
gptkb:Mannitol_Injection
|
| gptkbp:bfsLayer |
6
|