Aminoacyl-tRNA synthetase

URI: https://gptkb.org/entity/Aminoacyl-tRNA_synthetase
GPTKB entity
Statements (30)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName aaRS
aminoacyl-tRNA ligase
gptkbp:discoveredBy gptkb:Paul_Zamecnik
gptkbp:EC_number 6.1.1.-
gptkbp:errorDetection proofreading activity
gptkbp:formsComplexWith multi-synthetase complex
gptkbp:foundIn all living organisms
gptkbp:function catalyzes attachment of amino acid to tRNA
gptkbp:GO_term gptkb:GO:0004812
gptkbp:hasSpecificityFor corresponding tRNA
one amino acid
gptkbp:hasType gptkb:class_II_aminoacyl-tRNA_synthetase
gptkb:class_I_aminoacyl-tRNA_synthetase
gptkbp:involvedIn gptkb:translator
gptkbp:locale gptkb:cytoplasm
mitochondria
gptkbp:mutationAssociatedWith human diseases
gptkbp:numberOfTypesInHumans 20
gptkbp:product gptkb:aminoacyl-tRNA
gptkbp:requires gptkb:ATP
protein biosynthesis
gptkbp:studiedIn structural biology
gptkbp:substrate gptkb:amino_acid_transporter
tRNA
gptkbp:target antibiotics
antifungal agents
gptkbp:bfsParent gptkb:ACS
gptkbp:bfsLayer 5
https://www.w3.org/2000/01/rdf-schema#label Aminoacyl-tRNA synthetase