Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
biological assay
|
| gptkbp:alternativeTo |
animal testing for mutagenicity
|
| gptkbp:appliesTo |
environmental monitoring
genetic toxicology pharmaceutical safety testing |
| gptkbp:category |
genetic assay
|
| gptkbp:detects |
frameshift mutations
base-pair substitutions mutagenic potential of chemical compounds |
| gptkbp:developedBy |
gptkb:Bruce_Ames
|
| gptkbp:firstDescribed |
1973
|
| https://www.w3.org/2000/01/rdf-schema#label |
Ames test
|
| gptkbp:involves |
bacterial reverse mutation
|
| gptkbp:limitation |
false positives possible
not all carcinogens are mutagenic not all mutagens are detected |
| gptkbp:mayInclude |
liver extract (S9 mix)
|
| gptkbp:namedAfter |
gptkb:Bruce_Ames
|
| gptkbp:organism |
gptkb:Salmonella_typhimurium
gptkb:Bacteria |
| gptkbp:regulates |
gptkb:OECD_guidelines
FDA guidelines |
| gptkbp:relatedTo |
carcinogenicity
|
| gptkbp:requires |
histidine-deficient medium
|
| gptkbp:usedFor |
detecting mutagenicity
|
| gptkbp:bfsParent |
gptkb:TA-98
|
| gptkbp:bfsLayer |
5
|