|
gptkbp:instanceOf
|
gptkb:neurodegenerative_disease
|
|
gptkbp:affects
|
brain
|
|
gptkbp:alsoKnownAs
|
gptkb:AD
|
|
gptkbp:averageSpeed
|
8-10 years after diagnosis
|
|
gptkbp:awarenessEvent
|
World Alzheimer’s Day
|
|
gptkbp:awarenessMonth
|
September
|
|
gptkbp:characterizedBy
|
behavioral changes
cognitive decline
progressive memory loss
|
|
gptkbp:diagnosedBy
|
biomarker analysis
brain imaging
clinical assessment
neuropsychological testing
|
|
gptkbp:firstDescribed
|
gptkb:Alois_Alzheimer
1906
|
|
gptkbp:hasNoCure
|
true
|
|
gptkbp:ICD-10_code
|
gptkb:G30
|
|
gptkbp:MeSH_ID
|
gptkb:D000544
|
|
gptkbp:mostCommonCauseOf
|
gptkb:dementia
|
|
gptkbp:OMIM
|
104300
|
|
gptkbp:pathology
|
amyloid plaques
neurofibrillary tangles
neuronal loss
|
|
gptkbp:prevalence
|
millions affected worldwide
most common in people over 65
|
|
gptkbp:prognosis
|
progressive and fatal
|
|
gptkbp:researchInterest
|
biomarkers
disease-modifying therapies
genetics
prevention
|
|
gptkbp:riskFactor
|
gptkb:cardiovascular_disease
gptkb:APOE_ε4_allele
age
family history
genetic factors
head injury
|
|
gptkbp:symptom
|
behavioral issues
confusion
difficulty with language
disorientation
loss of motivation
memory loss
mood swings
self-neglect
|
|
gptkbp:treatment
|
gptkb:memantine
acetylcholinesterase inhibitors
behavioral therapy
supportive care
|
|
gptkbp:bfsParent
|
gptkb:Glenn_Biggs_Institute_for_Alzheimer’s_&_Neurodegenerative_Diseases
gptkb:Coach_Broyles’_Playbook_for_Alzheimer’s_Caregivers
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Alzheimer’s disease
|