Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
Genetic disorder
|
| gptkbp:affects |
Hemoglobin production
|
| gptkbp:causedBy |
Mutations in HBA1 gene
Mutations in HBA2 gene |
| gptkbp:complication |
Splenomegaly
Iron overload Hydrops fetalis |
| gptkbp:diagnosedBy |
Genetic testing
Blood test |
| gptkbp:firstDescribed |
1960s
|
| https://www.w3.org/2000/01/rdf-schema#label |
Alpha Thalassemia
|
| gptkbp:inheritance |
Autosomal recessive
|
| gptkbp:namedAfter |
Thalassa (Greek for sea)
|
| gptkbp:prevalence |
High in Africa
High in Mediterranean region High in Southeast Asia |
| gptkbp:subspecies |
Hemoglobin H disease
Alpha thalassemia trait Hemoglobin Bart's hydrops fetalis |
| gptkbp:symptom |
gptkb:anemia
Fatigue Jaundice Pale skin |
| gptkbp:treatment |
gptkb:Bone_marrow_transplant
Blood transfusion Folic acid supplements |
| gptkbp:bfsParent |
gptkb:Target_Cells
|
| gptkbp:bfsLayer |
8
|