|
gptkbp:instanceOf
|
gptkb:drug
|
|
gptkbp:administrationFrequency
|
once weekly
|
|
gptkbp:approvalYear
|
2003
|
|
gptkbp:ATCCode
|
A16AB05
|
|
gptkbp:CASNumber
|
104143-89-1
|
|
gptkbp:form
|
solution for infusion
|
|
gptkbp:genericName
|
gptkb:laronidase
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Aldurazyme
|
|
gptkbp:indication
|
gptkb:Hurler-Scheie_syndrome
gptkb:Hurler_syndrome
gptkb:Scheie_syndrome
|
|
gptkbp:KEGGID
|
D03141
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:manufacturer
|
gptkb:Sanofi_Genzyme
gptkb:BioMarin_Pharmaceutical
|
|
gptkbp:mechanismOfAction
|
enzyme replacement therapy
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:product
|
gptkb:recombinant_human_alpha-L-iduronidase
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201562
DB00095
|
|
gptkbp:routeOfAdministration
|
intravenous
|
|
gptkbp:RxCUI
|
213022
|
|
gptkbp:sideEffect
|
fever
nausea
vomiting
headache
allergic reaction
rash
|
|
gptkbp:storage
|
2-8°C
|
|
gptkbp:UNII
|
9I2K2V784M
|
|
gptkbp:usedFor
|
gptkb:Mucopolysaccharidosis_I
|
|
gptkbp:bfsParent
|
gptkb:Genzyme
gptkb:Genzyme_(2011)
gptkb:赛诺菲
|
|
gptkbp:bfsLayer
|
6
|