|
gptkbp:instance_of
|
gptkb:pharmaceuticals
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:atccode
|
L03 AB02
|
|
gptkbp:availability
|
prescription only
|
|
gptkbp:brand
|
gptkb:Actimmune
|
|
gptkbp:category
|
gptkb:unknown
Category C
|
|
gptkbp:class
|
biologic response modifier
|
|
gptkbp:clinical_trial
|
Phase III
|
|
gptkbp:clinical_use
|
gptkb:immunotherapy
|
|
gptkbp:code
|
00006-0001
|
|
gptkbp:contraindication
|
hypersensitivity to interferon gamma-1b
|
|
gptkbp:dosage_form
|
lyophilized powder for reconstitution
|
|
gptkbp:drug_interactions
|
none reported
|
|
gptkbp:duration
|
varies by condition
|
|
gptkbp:effective_date
|
1990-11-09
|
|
gptkbp:financial_stability
|
expires after 24 hours at room temperature
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Actimmune
|
|
gptkbp:indication
|
treatment of infections
|
|
gptkbp:ingredients
|
gptkb:interferon_gamma-1b
|
|
gptkbp:is_monitored_by
|
liver function tests
complete blood count
renal function tests
|
|
gptkbp:lifespan
|
approximately 2 hours
|
|
gptkbp:manufacturer
|
gptkb:Inter_Mune,_Inc.
|
|
gptkbp:market
|
conducted
|
|
gptkbp:marketed_as
|
gptkb:Canada
gptkb:European_Union
gptkb:United_States
|
|
gptkbp:mechanism_of_action
|
modulates immune response
|
|
gptkbp:packaging
|
vial
|
|
gptkbp:patient_education
|
storage requirements
importance of adherence to therapy
recognizing side effects
proper injection technique
when to seek medical attention
|
|
gptkbp:patient_population
|
children and adults
provided with prescription
|
|
gptkbp:pharmacokinetics
|
subcutaneous absorption
|
|
gptkbp:previous_name
|
gptkb:interferon_gamma-1b
|
|
gptkbp:price
|
varies by pharmacy
|
|
gptkbp:provides_guidance_on
|
followed for administration
|
|
gptkbp:reconstitution_instructions
|
dilute with sterile water
|
|
gptkbp:requires
|
available
|
|
gptkbp:research
|
ongoing
|
|
gptkbp:rounds
|
renal
|
|
gptkbp:route_of_administration
|
subcutaneous injection
|
|
gptkbp:safety_measures
|
monitor for signs of infection
|
|
gptkbp:service_frequency
|
3 times a week
|
|
gptkbp:side_effect
|
fatigue
headache
nausea
injection site reactions
autoimmune disorders
flu-like symptoms
|
|
gptkbp:storage
|
refrigerated
|
|
gptkbp:used_for
|
chronic granulomatous disease
severe malignant osteopetrosis
|
|
gptkbp:bfsParent
|
gptkb:Horizon_Therapeutics
|
|
gptkbp:bfsLayer
|
5
|