Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
IBAT
Ileal Bile Acid Transporter |
| gptkbp:encodedBy |
SLC10A2 gene
|
| gptkbp:fullName |
Apical Sodium-dependent Bile Acid Transporter
|
| gptkbp:function |
transports bile acids from the intestinal lumen into enterocytes
|
| gptkbp:gene |
gptkb:SLC10A2
|
| https://www.w3.org/2000/01/rdf-schema#label |
ASBT
|
| gptkbp:inhibitedBy |
elobixibat
odevixibat |
| gptkbp:locatedOnChromosome |
chromosome 13q33
|
| gptkbp:location |
apical membrane of ileal enterocytes
|
| gptkbp:organism |
gptkb:human
gptkb:mouse right |
| gptkbp:publicTransit |
gptkb:solute_carrier_family
|
| gptkbp:significance |
mutations can cause primary bile acid malabsorption
target for drugs treating bile acid diarrhea |
| gptkbp:structureType |
integral membrane protein
|
| gptkbp:substrate |
bile acids
|
| gptkbp:UniProtID |
gptkb:Q12908
|
| gptkbp:bfsParent |
gptkb:SLC10A2
gptkb:Sodium/bile_acid_cotransporter |
| gptkbp:bfsLayer |
8
|