APC gene mutation

GPTKB entity

Statements (63)
Predicate Object
gptkbp:instance_of gptkb:physicist
gptkbp:affects quality of life
treatment response
patient prognosis
tumor suppressor gene
gptkbp:can_be increased healthcare costs
genetic counseling recommendations
multiple polyps in the colon
gptkbp:can_lead_to gptkb:healthcare_organization
hereditary cancer syndromes
psychosocial impacts
advancements in oncology
extraintestinal manifestations
gptkbp:caused_by desmoid tumors
inherited genetic changes
gptkbp:descendant one or both parents
gptkbp:focuses_on clinical trials
genetic research
patient education efforts
https://www.w3.org/2000/01/rdf-schema#label APC gene mutation
gptkbp:influence treatment decisions
gptkbp:is_associated_with gptkb:attenuated_familial_adenomatous_polyposis
gptkb:Familial_Adenomatous_Polyposis
genetic predisposition
increased mortality risk
genetic heterogeneity
increased surveillance recommendations
gptkbp:is_characterized_by loss of function
gptkbp:is_essential_for personalized medicine
family planning decisions
gptkbp:is_found_in various populations
gptkbp:is_influenced_by environmental factors
gptkbp:is_involved_in cell cycle regulation
molecular diagnostics
Wnt signaling pathway
pathway dysregulation
gptkbp:is_linked_to epigenetic changes
clinical outcomes
family history of cancer
adenomatous polyps
gptkbp:is_part_of research studies
cancer predisposition syndromes
multigene panels
gptkbp:is_recognized_by gptkb:municipality
DNA sequencing
gptkbp:is_related_to lifestyle factors
gptkbp:is_studied_in gptkb:physicist
cancer research
biomarker development
gptkbp:issues healthcare providers
gptkbp:managed_by preventive surgery
gptkbp:recognizes genetic testing
gptkbp:requires regular colonoscopy screening
gptkbp:research tumorigenesis
gptkbp:risk_factor other cancers
gptkbp:subject ethical considerations
scientific publications
public health discussions
gptkbp:targets novel therapies
gptkbp:type_of germline mutation
gptkbp:was_a_factor_in cancer prevention strategies
gptkbp:bfsParent gptkb:Colorectal_cancer
gptkbp:bfsLayer 5