Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
ADNP homeobox 1
ANDP Activity Dependent Neuroprotector Protein HVDAS NAP protein gene |
| gptkbp:associatedWith |
gptkb:autism_spectrum_disorder
intellectual disability ADNP syndrome Helsmoortel-Van der Aa syndrome |
| gptkbp:biologicalProcess |
gptkb:synaptic_plasticity
cell proliferation cell survival regulation of apoptosis brain development neuronal differentiation regulation of cytoskeleton neuroprotection transcriptional repression axon guidance chromatin remodeling microtubule stabilization |
| gptkbp:contains |
homeobox domain
|
| gptkbp:discoveredBy |
Ilan Gozes
|
| gptkbp:encodes |
ADNP protein
|
| gptkbp:Entrez_Gene_ID |
23394
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
gptkb:placenta brain heart |
| gptkbp:firstDescribed |
1999
|
| gptkbp:fullName |
Activity-dependent neuroprotector homeobox
|
| gptkbp:function |
neurodevelopment
transcription regulation |
| gptkbp:HGNC_ID |
19158
|
| https://www.w3.org/2000/01/rdf-schema#label |
ADNP
|
| gptkbp:interactsWith |
gptkb:SWI/SNF_chromatin_remodeling_complex
heterochromatin protein 1 (HP1) |
| gptkbp:length |
1102 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:20q13.13
|
| gptkbp:mutationAssociatedWith |
de novo
ADNP syndrome |
| gptkbp:OMIM |
611386
|
| gptkbp:orthologInMouse |
Adnp
|
| gptkbp:orthologInZebrafish |
adnpa
adnpb |
| gptkbp:regulates |
gene expression
microtubule dynamics neural differentiation |
| gptkbp:UniProtID |
Q9H2P0
|
| gptkbp:bfsParent |
gptkb:Arab_Democratic_Nasserist_Party
|
| gptkbp:bfsLayer |
7
|