5-alpha-reductase inhibitors
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:ATCCode |
G04CB
|
| gptkbp:contraindication |
pregnancy
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:effect |
reduce dihydrotestosterone levels
|
| gptkbp:example |
gptkb:dutasteride
gptkb:finasteride |
| gptkbp:mechanismOfAction |
inhibit 5-alpha-reductase enzyme
|
| gptkbp:notableBrand |
gptkb:Propecia
gptkb:Avodart |
| gptkbp:pregnancyCategory |
X
|
| gptkbp:prescribes |
gptkb:urologist
gptkb:dermatologist |
| gptkbp:regulates |
testosterone metabolism
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
decreased libido
gynecomastia erectile dysfunction |
| gptkbp:usedFor |
gptkb:benign_prostatic_hyperplasia
androgenetic alopecia |
| gptkbp:bfsParent |
gptkb:benign_prostatic_hyperplasia
|
| gptkbp:bfsLayer |
8
|
| http://www.w3.org/2000/01/rdf-schema#label |
5-alpha-reductase inhibitors
|