4-hydroxytamoxifen

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
selective estrogen receptor modulator
gptkbp:CASNumber 68047-06-3
gptkbp:chemicalFormula C26H29NO2
gptkbp:drugClass antineoplastic agent
antiestrogen
gptkbp:hasInChIKey NKANXQFJJICGDU-QPLCGJKRSA-N
gptkbp:hasSMILES CN(C)CCOc1ccc(cc1)/C(=C(/c2ccccc2)c3ccccc3)/O
https://www.w3.org/2000/01/rdf-schema#label 4-hydroxytamoxifen
gptkbp:is_active_metabolite_of gptkb:tamoxifen
gptkbp:IUPACName (Z)-2-[4-(1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
gptkbp:meltingPoint 138-140°C
gptkbp:metabolism gptkb:tamoxifen
gptkbp:molecularWeight 387.51 g/mol
gptkbp:PubChem_CID gptkb:CHEMBL123
62742
gptkbp:target estrogen receptor alpha
estrogen receptor beta
gptkbp:UNII 1A6N6GBZ4U
gptkbp:used_in gptkb:Cre-ERT2_recombinase_systems
breast cancer research
gptkbp:bfsParent gptkb:tamoxifen
gptkbp:bfsLayer 6