Statements (20)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
oxysterol
cholesterol metabolite |
| gptkbp:affects |
estrogen receptor signaling
liver X receptor (LXR) signaling |
| gptkbp:associatedWith |
atherosclerosis
breast cancer progression |
| gptkbp:CASNumber |
20380-11-4
|
| gptkbp:chemicalFormula |
C27H46O2
|
| gptkbp:foundIn |
human plasma
|
| https://www.w3.org/2000/01/rdf-schema#label |
27-hydroxycholesterol
|
| gptkbp:IUPACName |
(25R)-cholest-5-ene-3β,27-diol
|
| gptkbp:metabolism |
CYP7B1
|
| gptkbp:producedBy |
CYP27A1
|
| gptkbp:role |
endogenous selective estrogen receptor modulator
intermediate in bile acid biosynthesis |
| gptkbp:synonym |
(25R)-cholest-5-ene-3β,27-diol
27-OHC cholest-5-ene-3β,27-diol |
| gptkbp:bfsParent |
gptkb:Liver_X_Receptor
|
| gptkbp:bfsLayer |
7
|