186692-46-6

URI: https://gptkb.org/entity/186692-46-6
GPTKB entity
Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:chemical_compound
gptkbp:approvalYear 2015
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode L01EB37
gptkbp:CASNumber gptkb:186692-46-6
gptkbp:developedBy gptkb:AstraZeneca
gptkbp:hasMolecularFormula C28H33N7O2
gptkbp:hasUNII 7A5I1C1W3F
https://www.w3.org/2000/01/rdf-schema#label 186692-46-6
gptkbp:indication gptkb:non-small_cell_lung_cancer
gptkbp:isApprovedDrug true
gptkbp:IUPACName gptkb:N-(2-{2-Dimethylamino)ethyl}-4-methoxy-5-{[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino}phenyl)prop-2-enamide
gptkbp:marketedAs gptkb:Tagrisso
gptkbp:mechanismOfAction gptkb:EGFR_tyrosine_kinase_inhibitor
gptkbp:molecularWeight 499.6 g/mol
gptkbp:PubChem_CID gptkb:DB09330
CHEMBL3185146
71496458
gptkbp:routeOfAdministration oral
gptkbp:synonym gptkb:AZD9291
gptkb:Osimertinib
gptkbp:bfsParent gptkb:roscovitine
gptkbp:bfsLayer 6