Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
|
| gptkbp:approvalYear |
2015
|
| gptkbp:approvedBy |
gptkb:FDA
gptkb:EMA |
| gptkbp:ATCCode |
L01EB04
|
| gptkbp:CASNumber |
gptkb:152121-30-7
|
| gptkbp:hasInChIKey |
YQEZLKZALYSWHR-UHFFFAOYSA-N
|
| gptkbp:hasMolecularFormula |
C28H33N7O2
|
| gptkbp:hasSMILES |
COC1=CC=CC(=C1)C2=NC3=CC=CC=C3N=C2N4CCN(CC4)C(=O)C5=CC=CC=C5N
|
| gptkbp:hasUNII |
3C06UO638K
|
| https://www.w3.org/2000/01/rdf-schema#label |
152121-30-7
|
| gptkbp:KEGGID |
D10568
|
| gptkbp:legalStatus |
prescription only
patented |
| gptkbp:marketedAs |
gptkb:AstraZeneca
|
| gptkbp:mechanismOfAction |
gptkb:EGFR_tyrosine_kinase_inhibitor
|
| gptkbp:molecularWeight |
499.61 g/mol
|
| gptkbp:name |
gptkb:Osimertinib
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:PubChem_CID |
gptkb:DB09330
CHEMBL3185146 71512363 58128237 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
diarrhea fatigue rash stomatitis |
| gptkbp:synonym |
gptkb:Tagrisso
gptkb:AZD9291 |
| gptkbp:usedFor |
treatment of non-small cell lung cancer
|
| gptkbp:bfsParent |
gptkb:SB203580
|
| gptkbp:bfsLayer |
7
|