Triple
T6004834
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | C9orf72 |
E133683
|
entity |
| Predicate | formsComplexWith |
P6653
|
FINISHED |
| Object |
SMCR8-WDR41 complex
The SMCR8-WDR41 complex is a protein assembly that partners with C9orf72 to regulate autophagy and lysosomal function, particularly in the context of neurodegenerative disease mechanisms.
|
E561102
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: SMCR8-WDR41 complex | Statement: [C9orf72, formsComplexWith, SMCR8-WDR41 complex]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: SMCR8-WDR41 complex Context triple: [C9orf72, formsComplexWith, SMCR8-WDR41 complex]
-
A.
W3/W4/W5 complex
The W3/W4/W5 complex is a large, neighboring group of massive star-forming regions in the Perseus Arm of the Milky Way, notable for its active stellar nurseries and intricate nebular structures.
-
B.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
C.
The O2 complex
The O2 complex is a large entertainment district in London featuring the O2 Arena, cinemas, restaurants, bars, and various leisure and retail facilities housed under the iconic dome structure.
-
D.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
E.
CD38
CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: SMCR8-WDR41 complex Triple: [C9orf72, formsComplexWith, SMCR8-WDR41 complex]
Generated description
The SMCR8-WDR41 complex is a protein assembly that partners with C9orf72 to regulate autophagy and lysosomal function, particularly in the context of neurodegenerative disease mechanisms.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: SMCR8-WDR41 complex Target entity description: The SMCR8-WDR41 complex is a protein assembly that partners with C9orf72 to regulate autophagy and lysosomal function, particularly in the context of neurodegenerative disease mechanisms.
-
A.
W3/W4/W5 complex
The W3/W4/W5 complex is a large, neighboring group of massive star-forming regions in the Perseus Arm of the Milky Way, notable for its active stellar nurseries and intricate nebular structures.
-
B.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
C.
The O2 complex
The O2 complex is a large entertainment district in London featuring the O2 Arena, cinemas, restaurants, bars, and various leisure and retail facilities housed under the iconic dome structure.
-
D.
Cdc28
Cdc28 is the major cyclin-dependent kinase in budding yeast that drives progression through the cell cycle by phosphorylating key regulatory proteins.
-
E.
CD38
CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69c00872444c8190bfaf1739dcec765c |
completed | March 22, 2026, 3:19 p.m. |
| NER | Named-entity recognition | batch_69c04f10d18081908c351170b7f58d3d |
completed | March 22, 2026, 8:20 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69c1088f5c84819094e4696c24c4dd79 |
completed | March 23, 2026, 9:31 a.m. |
| NEDg | Description generation | batch_69c1099f00f88190a5f1f0fafbb679c2 |
completed | March 23, 2026, 9:36 a.m. |
| NED2 | Entity disambiguation (via description) | batch_69c10a2ffdcc8190bfeebc59d98b2b29 |
completed | March 23, 2026, 9:38 a.m. |
Created at: March 22, 2026, 4:06 p.m.