Triple
T32226585
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | irinotecan |
E823218
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | topoisomerase I inhibitor |
C59323
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: topoisomerase I inhibitor Context triple: [irinotecan, instanceOf, topoisomerase I inhibitor]
-
A.
PARP inhibitor
A PARP inhibitor is a targeted anticancer drug that blocks poly(ADP-ribose) polymerase enzymes to prevent DNA repair in tumor cells, leading to their death, particularly in cancers with existing DNA repair defects such as BRCA-mutated tumors.
-
B.
mitotic inhibitor
A mitotic inhibitor is a substance that disrupts or halts cell division by interfering with the processes of mitosis, often used in cancer therapy to prevent rapidly dividing tumor cells from proliferating.
-
C.
CDK4/6 inhibitor
A CDK4/6 inhibitor is a targeted anticancer drug that blocks cyclin-dependent kinases 4 and 6 to halt cell cycle progression from G1 to S phase, thereby inhibiting tumor cell proliferation.
-
D.
alkylating agent
An alkylating agent is a chemical compound that transfers alkyl groups to biological molecules, often DNA, leading to disruption of normal cellular function and frequently used in chemotherapy to kill rapidly dividing cells.
-
E.
tyrosine kinase inhibitor
A tyrosine kinase inhibitor is a drug that blocks the activity of tyrosine kinases—enzymes involved in cell signaling pathways—to prevent uncontrolled cell growth and proliferation, commonly used in cancer therapy.
- F. None of above. chosen
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69f3490b4f948190b99e4f999f5be25f |
completed | April 30, 2026, 12:20 p.m. |
Created at: May 1, 2026, 12:38 a.m.