topoisomerase I inhibitor
C59323
concept
A topoisomerase I inhibitor is a drug that blocks the activity of the topoisomerase I enzyme, preventing DNA strand relaxation during replication and transcription and thereby inducing DNA damage and cell death, particularly in rapidly dividing cells.
All labels observed (2)
| Label | Occurrences |
|---|---|
| camptothecin derivative | 1 |
| topoisomerase I inhibitor canonical | 1 |
Description generation (CDg)
The one-sentence description above was generated by prompting gpt-5.1 with the class name and this instruction.
Instruction
generate a one-sentence description for a given conceptual class. # Response Format Return only the sentence: "Description: [one-sentence description of the conceptional class]"
Input
Class: topoisomerase I inhibitor
Generated description
A topoisomerase I inhibitor is a drug that blocks the activity of the topoisomerase I enzyme, preventing DNA strand relaxation during replication and transcription and thereby inducing DNA damage and cell death, particularly in rapidly dividing cells.
Instances (1)
| Instance | Via concept surface |
|---|---|
| irinotecan | — |