Triple

T22871271
Position Surface form Disambiguated ID Type / Status
Subject CYP2C9 E567200 entity
Predicate hasPolymorphism P92783 FINISHED
Object CYP2C9*3
CYP2C9*3 is a common reduced-function genetic variant of the CYP2C9 enzyme that significantly affects the metabolism of various drugs, including warfarin and certain NSAIDs.
 E567200 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CYP2C9*3 | Statement: [CYP2C9, hasPolymorphism, CYP2C9*3]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: CYP2C9*3
Context triple: [CYP2C9, hasPolymorphism, CYP2C9*3]
  • A. CYP2C9
    CYP2C9 is a liver enzyme of the cytochrome P450 family that plays a key role in metabolizing various drugs, including many nonsteroidal anti-inflammatory agents and anticoagulants.
  • B. CYP2C19
    CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
  • C. CYP3A5
    CYP3A5 is a liver-expressed cytochrome P450 enzyme that metabolizes various drugs and xenobiotics, contributing to interindividual variability in drug clearance.
  • D. CYP2D6
    CYP2D6 is a highly polymorphic cytochrome P450 enzyme that plays a major role in the metabolism of many drugs, contributing significantly to interindividual variability in drug response.
  • E. CYP1A2
    CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: CYP2C9*3
Triple: [CYP2C9, hasPolymorphism, CYP2C9*3]
Generated description
CYP2C9*3 is a common reduced-function genetic variant of the CYP2C9 enzyme that significantly affects the metabolism of various drugs, including warfarin and certain NSAIDs.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: CYP2C9*3
Target entity description: CYP2C9*3 is a common reduced-function genetic variant of the CYP2C9 enzyme that significantly affects the metabolism of various drugs, including warfarin and certain NSAIDs.
  • A. CYP2C9 chosen
    CYP2C9 is a liver enzyme of the cytochrome P450 family that plays a key role in metabolizing various drugs, including many nonsteroidal anti-inflammatory agents and anticoagulants.
  • B. CYP2C19
    CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
  • C. CYP3A5
    CYP3A5 is a liver-expressed cytochrome P450 enzyme that metabolizes various drugs and xenobiotics, contributing to interindividual variability in drug clearance.
  • D. CYP2D6
    CYP2D6 is a highly polymorphic cytochrome P450 enzyme that plays a major role in the metabolism of many drugs, contributing significantly to interindividual variability in drug response.
  • E. CYP1A2
    CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
  • F. None of above.

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e24589d8348190b96422d13a678bc1 completed April 17, 2026, 2:36 p.m.
NER Named-entity recognition batch_69f17f05c688819097ba3d24ea8e52f5 completed April 29, 2026, 3:46 a.m.
NED1 Entity disambiguation (via context triple) batch_6a0bb9b71db48190a8094cb27a11abd1 completed May 19, 2026, 1:15 a.m.
NEDg Description generation batch_6a0bbacbebe081909a1397d7cb67dce2 completed May 19, 2026, 1:20 a.m.
NED2 Entity disambiguation (via description) batch_6a0bbb3dee788190b7345daac34f307a completed May 19, 2026, 1:22 a.m.
Created at: April 17, 2026, 3:38 p.m.