Triple

T22796809
Position Surface form Disambiguated ID Type / Status
Subject LOXO-195 E564270 entity
Predicate targets P860 FINISHED
Object NTRK3 NE NERFINISHED

How this triple was built (3 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: NTRK3 | Statement: [LOXO-195, targets, NTRK3]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: NTRK3
Context triple: [LOXO-195, targets, NTRK3]
  • A. NTRK1
    NTRK1 is a proto-oncogene encoding the TRKA receptor tyrosine kinase, which mediates nerve growth factor signaling and can drive cancer when involved in gene fusions.
  • B. TRK
    TRK is the FAA location identifier for Truckee Tahoe Airport, a public airport serving the Truckee and Lake Tahoe region in California.
  • C. TRKB
    TRKB is a receptor tyrosine kinase encoded by the NTRK2 gene that plays a key role in neurotrophin signaling and neuronal development.
  • D. ERBB3
    ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
  • E. NR4A3
    NR4A3 is a nuclear receptor transcription factor involved in regulating gene expression linked to cell growth, differentiation, and oncogenic fusion events in certain cancers.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: NTRK3
Target entity description: NTRK3 is a gene encoding the TrkC receptor, a neurotrophin tyrosine kinase frequently involved in oncogenic fusions that drive certain cancers.
  • A. NTRK1
    NTRK1 is a proto-oncogene encoding the TRKA receptor tyrosine kinase, which mediates nerve growth factor signaling and can drive cancer when involved in gene fusions.
  • B. TRK
    TRK is the FAA location identifier for Truckee Tahoe Airport, a public airport serving the Truckee and Lake Tahoe region in California.
  • C. TRKB
    TRKB is a receptor tyrosine kinase encoded by the NTRK2 gene that plays a key role in neurotrophin signaling and neuronal development.
  • D. ERBB3
    ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
  • E. NR4A3
    NR4A3 is a nuclear receptor transcription factor involved in regulating gene expression linked to cell growth, differentiation, and oncogenic fusion events in certain cancers.
  • F. None of above. chosen

Provenance (2 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e2458185f88190b0045227ee420411 completed April 17, 2026, 2:36 p.m.
NER Named-entity recognition batch_69f17cd9b3c0819096050f43a829ec0d completed April 29, 2026, 3:36 a.m.
Created at: April 17, 2026, 3:30 p.m.