NTRK3
E1555611
UNEXPLORED
NTRK3 is a gene encoding the TrkC receptor, a neurotrophin tyrosine kinase frequently involved in oncogenic fusions that drive certain cancers.
All labels observed (1)
| Label | Occurrences |
|---|---|
| NTRK3 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T22796809 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: NTRK3 Context triple: [LOXO-195, targets, NTRK3]
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A.
NTRK1
NTRK1 is a proto-oncogene encoding the TRKA receptor tyrosine kinase, which mediates nerve growth factor signaling and can drive cancer when involved in gene fusions.
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B.
TRK
TRK is the FAA location identifier for Truckee Tahoe Airport, a public airport serving the Truckee and Lake Tahoe region in California.
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C.
TRKB
TRKB is a receptor tyrosine kinase encoded by the NTRK2 gene that plays a key role in neurotrophin signaling and neuronal development.
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D.
ERBB3
ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
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E.
NR4A3
NR4A3 is a nuclear receptor transcription factor involved in regulating gene expression linked to cell growth, differentiation, and oncogenic fusion events in certain cancers.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: NTRK3 Target entity description: NTRK3 is a gene encoding the TrkC receptor, a neurotrophin tyrosine kinase frequently involved in oncogenic fusions that drive certain cancers.
-
A.
NTRK1
NTRK1 is a proto-oncogene encoding the TRKA receptor tyrosine kinase, which mediates nerve growth factor signaling and can drive cancer when involved in gene fusions.
-
B.
TRK
TRK is the FAA location identifier for Truckee Tahoe Airport, a public airport serving the Truckee and Lake Tahoe region in California.
-
C.
TRKB
TRKB is a receptor tyrosine kinase encoded by the NTRK2 gene that plays a key role in neurotrophin signaling and neuronal development.
-
D.
ERBB3
ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
-
E.
NR4A3
NR4A3 is a nuclear receptor transcription factor involved in regulating gene expression linked to cell growth, differentiation, and oncogenic fusion events in certain cancers.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.