Triple

T22693141
Position Surface form Disambiguated ID Type / Status
Subject WDR41 E561101 entity
Predicate binds P1045 FINISHED
Object PIKfyve — NE NERFINISHED

How this triple was built (3 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: PIKfyve | Statement: [WDR41, binds, PIKfyve]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: PIKfyve
Context triple: [WDR41, binds, PIKfyve]
  • A. NPC1L1 transporter
    The NPC1L1 transporter is an intestinal membrane protein that mediates cholesterol absorption from the gut and is inhibited by the lipid-lowering drug ezetimibe.
  • B. PLCγ2
    PLCγ2 is a phospholipase C isoform that functions as a key signaling enzyme in immune cells, mediating receptor-induced calcium mobilization and downstream activation pathways.
  • C. Ezrin
    Ezrin is a Canadian music producer and songwriter best known for his work on landmark rock albums by artists such as Pink Floyd, Alice Cooper, and Kiss.
  • D. LDL receptor
    The LDL receptor is a cell-surface protein that binds and internalizes low-density lipoprotein particles, playing a central role in cholesterol homeostasis and cardiovascular disease risk.
  • E. Bruton tyrosine kinase
    Bruton tyrosine kinase is a key signaling enzyme in B cells that plays a crucial role in their development and function and is a major therapeutic target in certain blood cancers and autoimmune diseases.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07 
Target entity: PIKfyve
Target entity description: PIKfyve is a lipid kinase that synthesizes phosphatidylinositol 3,5-bisphosphate and plays a key role in endosomal trafficking and lysosomal function.
  • A. NPC1L1 transporter
    The NPC1L1 transporter is an intestinal membrane protein that mediates cholesterol absorption from the gut and is inhibited by the lipid-lowering drug ezetimibe.
  • B. PLCγ2
    PLCγ2 is a phospholipase C isoform that functions as a key signaling enzyme in immune cells, mediating receptor-induced calcium mobilization and downstream activation pathways.
  • C. Ezrin
    Ezrin is a Canadian music producer and songwriter best known for his work on landmark rock albums by artists such as Pink Floyd, Alice Cooper, and Kiss.
  • D. LDL receptor
    The LDL receptor is a cell-surface protein that binds and internalizes low-density lipoprotein particles, playing a central role in cholesterol homeostasis and cardiovascular disease risk.
  • E. Bruton tyrosine kinase
    Bruton tyrosine kinase is a key signaling enzyme in B cells that plays a crucial role in their development and function and is a major therapeutic target in certain blood cancers and autoimmune diseases.
  • F. None of above. chosen

Provenance (2 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69e2454d71b48190a1f80af9f82b6fcf completed April 17, 2026, 2:35 p.m.
NER Named-entity recognition batch_69f1789c6ae481908975b7d27e7624ac completed April 29, 2026, 3:18 a.m.
Created at: April 17, 2026, 3:13 p.m.