Triple
T22693115
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | SMCR8 |
E561100
|
entity |
| Predicate | participatesIn |
P149
|
FINISHED |
| Object | C9orf72–SMCR8–WDR41 complex |
—
|
NE NERFINISHED |
How this triple was built (2 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: C9orf72–SMCR8–WDR41 complex | Statement: [SMCR8, participatesIn, C9orf72–SMCR8–WDR41 complex]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: C9orf72–SMCR8–WDR41 complex Context triple: [SMCR8, participatesIn, C9orf72–SMCR8–WDR41 complex]
-
A.
SMCR8-WDR41 complex
chosen
The SMCR8-WDR41 complex is a protein assembly that partners with C9orf72 to regulate autophagy and lysosomal function, particularly in the context of neurodegenerative disease mechanisms.
-
B.
C9orf72
C9orf72 is a human gene whose hexanucleotide repeat expansions are the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
-
C.
Cajal bodies
Cajal bodies are dynamic nuclear suborganelles involved in the biogenesis and maturation of small nuclear ribonucleoproteins (snRNPs) and other RNA-processing factors.
-
D.
SMN complex
The SMN complex is a multiprotein assembly crucial for the biogenesis of small nuclear ribonucleoproteins (snRNPs) and proper pre-mRNA splicing, with key roles in motor neuron survival.
-
E.
TDP-43 proteinopathy
TDP-43 proteinopathy is a neurodegenerative condition characterized by abnormal aggregation and mislocalization of the TDP-43 protein, commonly implicated in disorders such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
Provenance (2 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
| NER | Named-entity recognition | batch_69f1789c6ae481908975b7d27e7624ac |
completed | April 29, 2026, 3:18 a.m. |
Created at: April 17, 2026, 3:13 p.m.