Triple
T22690150
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | CYP1A2 |
E561029
|
entity |
| Predicate | memberOf |
P10
|
FINISHED |
| Object |
cytochrome P450 superfamily
The cytochrome P450 superfamily is a large and diverse group of heme-containing enzymes that catalyze the oxidation of a wide variety of endogenous compounds and xenobiotics, playing key roles in drug metabolism and biosynthesis of hormones and lipids.
|
E1549311
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: cytochrome P450 superfamily | Statement: [CYP1A2, memberOf, cytochrome P450 superfamily]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: cytochrome P450 superfamily Context triple: [CYP1A2, memberOf, cytochrome P450 superfamily]
-
A.
CYP3A4
CYP3A4 is a major human liver and intestinal enzyme of the cytochrome P450 family responsible for metabolizing a wide range of drugs and xenobiotics.
-
B.
CYP1A2
CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
-
C.
cytochrome P450 reductase
Cytochrome P450 reductase is a flavoprotein enzyme that transfers electrons from NADPH to cytochrome P450 enzymes, enabling their role in drug metabolism and biosynthesis of endogenous compounds.
-
D.
CYP2J2
CYP2J2 is a human cytochrome P450 enzyme primarily expressed in the heart and other tissues, involved in the metabolism of various drugs and endogenous fatty acids.
-
E.
CYP2B6
CYP2B6 is a human liver cytochrome P450 enzyme that plays a key role in the metabolism of various drugs and xenobiotics.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: cytochrome P450 superfamily Triple: [CYP1A2, memberOf, cytochrome P450 superfamily]
Generated description
The cytochrome P450 superfamily is a large and diverse group of heme-containing enzymes that catalyze the oxidation of a wide variety of endogenous compounds and xenobiotics, playing key roles in drug metabolism and biosynthesis of hormones and lipids.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: cytochrome P450 superfamily Target entity description: The cytochrome P450 superfamily is a large and diverse group of heme-containing enzymes that catalyze the oxidation of a wide variety of endogenous compounds and xenobiotics, playing key roles in drug metabolism and biosynthesis of hormones and lipids.
-
A.
CYP3A4
CYP3A4 is a major human liver and intestinal enzyme of the cytochrome P450 family responsible for metabolizing a wide range of drugs and xenobiotics.
-
B.
CYP1A2
CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
-
C.
cytochrome P450 reductase
Cytochrome P450 reductase is a flavoprotein enzyme that transfers electrons from NADPH to cytochrome P450 enzymes, enabling their role in drug metabolism and biosynthesis of endogenous compounds.
-
D.
CYP2J2
CYP2J2 is a human cytochrome P450 enzyme primarily expressed in the heart and other tissues, involved in the metabolism of various drugs and endogenous fatty acids.
-
E.
CYP2B6
CYP2B6 is a human liver cytochrome P450 enzyme that plays a key role in the metabolism of various drugs and xenobiotics.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
| NER | Named-entity recognition | batch_69f1789a1fd08190bce5fa0babe695d3 |
completed | April 29, 2026, 3:18 a.m. |
| NED1 | Entity disambiguation (via context triple) | batch_6a0b73fa5a648190b90ba303d1fe2397 |
completed | May 18, 2026, 8:18 p.m. |
| NEDg | Description generation | batch_6a0b7755eb048190ba1657a9a09bc24b |
completed | May 18, 2026, 8:32 p.m. |
| NED2 | Entity disambiguation (via description) | batch_6a0b780c0a4c8190b51b50c1e0e1a114 |
completed | May 18, 2026, 8:35 p.m. |
Created at: April 17, 2026, 3:13 p.m.