Triple

T20125693
Position Surface form Disambiguated ID Type / Status
Subject Fentanyl E490748 entity
Predicate actsOnReceptor P9769 FINISHED
Object mu-opioid receptor
The mu-opioid receptor is a G protein–coupled receptor in the nervous system that mediates the powerful analgesic and euphoric effects of opioids as well as their major side effects, including respiratory depression and dependence.
E1412779 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: mu-opioid receptor | Statement: [Fentanyl, actsOnReceptor, mu-opioid receptor]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: mu-opioid receptor
Context triple: [Fentanyl, actsOnReceptor, mu-opioid receptor]
  • A. CB1 receptor
    The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
  • B. CB2 receptor
    The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
  • C. M2 muscarinic acetylcholine receptor
    The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
  • D. somatostatin receptor
    A somatostatin receptor is a G protein–coupled membrane receptor that binds the peptide hormone somatostatin to inhibit hormone secretion and modulate neurotransmission and cell proliferation.
  • E. NMDA receptor
    The NMDA receptor is a glutamate-activated ion channel in the brain that plays a key role in synaptic plasticity, learning, and memory, and is implicated in various neurological and psychiatric disorders.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: mu-opioid receptor
Triple: [Fentanyl, actsOnReceptor, mu-opioid receptor]
Generated description
The mu-opioid receptor is a G protein–coupled receptor in the nervous system that mediates the powerful analgesic and euphoric effects of opioids as well as their major side effects, including respiratory depression and dependence.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: mu-opioid receptor
Target entity description: The mu-opioid receptor is a G protein–coupled receptor in the nervous system that mediates the powerful analgesic and euphoric effects of opioids as well as their major side effects, including respiratory depression and dependence.
  • A. CB1 receptor
    The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
  • B. CB2 receptor
    The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
  • C. M2 muscarinic acetylcholine receptor
    The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
  • D. somatostatin receptor
    A somatostatin receptor is a G protein–coupled membrane receptor that binds the peptide hormone somatostatin to inhibit hormone secretion and modulate neurotransmission and cell proliferation.
  • E. NMDA receptor
    The NMDA receptor is a glutamate-activated ion channel in the brain that plays a key role in synaptic plasticity, learning, and memory, and is implicated in various neurological and psychiatric disorders.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69da62651a0c8190a3e05e95e056a66b completed April 11, 2026, 3:01 p.m.
NER Named-entity recognition batch_69e6674223008190827c454fe7ac86f4 completed April 20, 2026, 5:49 p.m.
NED1 Entity disambiguation (via context triple) batch_6a082dd9c1448190aa4038899470daf0 completed May 16, 2026, 8:42 a.m.
NEDg Description generation batch_6a082e93a1e88190bac5daae12ece9f2 completed May 16, 2026, 8:45 a.m.
NED2 Entity disambiguation (via description) batch_6a082f334dd481908edb6ea3ae07e0a7 completed May 16, 2026, 8:47 a.m.
Created at: April 11, 2026, 11:31 p.m.