Triple

Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).

Phrase: mu-opioid receptor | Statement: [Fentanyl, actsOnReceptor, mu-opioid receptor]

Target entity: mu-opioid receptor
Context triple: [Fentanyl, actsOnReceptor, mu-opioid receptor]

• A. CB1 receptor
  The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
• B. CB2 receptor
  The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
• C. M2 muscarinic acetylcholine receptor
  The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
• D. somatostatin receptor
  A somatostatin receptor is a G protein–coupled membrane receptor that binds the peptide hormone somatostatin to inhibit hormone secretion and modulate neurotransmission and cell proliferation.
• E. NMDA receptor
  The NMDA receptor is a glutamate-activated ion channel in the brain that plays a key role in synaptic plasticity, learning, and memory, and is implicated in various neurological and psychiatric disorders.
• F. None of above. chosen
• G. Unsure - the case is ambiguous/there is not enough information to decide.

Target entity: mu-opioid receptor
Target entity description: The mu-opioid receptor is a G protein–coupled receptor in the nervous system that mediates the powerful analgesic and euphoric effects of opioids as well as their major side effects, including respiratory depression and dependence.

• A. CB1 receptor
  The CB1 receptor is a G protein–coupled cannabinoid receptor in the brain and nervous system that mediates most of the psychoactive effects of cannabis.
• B. CB2 receptor
  The CB2 receptor is a cannabinoid receptor primarily expressed in immune and peripheral tissues, where it modulates inflammation and immune responses and serves as a key target of compounds like THC.
• C. M2 muscarinic acetylcholine receptor
  The M2 muscarinic acetylcholine receptor is a G protein–coupled receptor subtype primarily found in the heart, where it mediates parasympathetic (vagal) effects such as slowing heart rate and reducing contractility.
• D. somatostatin receptor
  A somatostatin receptor is a G protein–coupled membrane receptor that binds the peptide hormone somatostatin to inhibit hormone secretion and modulate neurotransmission and cell proliferation.
• E. NMDA receptor
  The NMDA receptor is a glutamate-activated ion channel in the brain that plays a key role in synaptic plasticity, learning, and memory, and is implicated in various neurological and psychiatric disorders.
• F. None of above. chosen